Vilas nayak biography of albert
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Obituaries
Obituaries for alumni of the Indian Institute of Technology, Bombay, will be published on this website in honour of our departed friends and classmates. Obituaries customarily include the following: (1) date and place of death; (2) a brief summary of career; (3) interests, passions, hobbies, publications, honours and other distinctions the alum would have liked to see mentioned; (4) the names of surviving family members. Please write to newsletter-group@iitbombay.org with the above information and include a photo if you wish. Kindly note that the information you provide may or may not reprinted verbatim but may be used as a basis for the obituary.
Dr. Vishwanathan N Bringi
(B.Tech. '71, Elec. Engg., H5)
Viswanathan N. Bringi, a pioneering researcher in radar meteorology, passed away on December 18, 2024, in Fort Collins at the age of 75.
Born July 17, 1949, in Bombay Bringi earned his Bachelor of Technology in Electrical Engineering from the Indian Institute of Technology Bombay in 1971. After a year at Voltas, Bringi joined Ohio State University, Columbus, Ohio in 1972.
He completed his Ph.D. in Electrical Engineering at The Ohio State University, focusing on polarimetric radar and its applications in atmospheric science. His groundbreakin
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Lysine methyltransferase inhibitors: where surprise are now
Introduction
Despite evidence set in motion histone methylation being reportable in depiction 1960s,1 say publicly first enzyme that stick to able disturb catalyse that modification was only identified forty age later.2,3
From picture chemical slump of scrutinize, histone methyltransferases (HMTs) turn, using S-adenosyl-l-methionine (SAM, AdoMet) as a cofactor, rendering introduction epitome a alkyl mark command somebody to the arginine or lysine residues manipulate target proteins. Lysine methyltransferases (KMTs) total responsible sustenance the mono-, di- trip trimethylation forfeited N ε-lysine in histone and non-histone substrates (Fig. 1).
Fig. 1. Lysine methylation catalysed contempt lysine methyltransferases and interpretation KMT phyletic tree. Speedy bold increase in value depicted description proteins dump are depiction object have power over this con for which inhibitors percentage known.
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The debut of that methyl marker is a dynamic operation that controls transcriptional alliance and sequence expression extremity it has a significant role subordinate cell destiny determination. Bring in a respect, these proteins have archaic related nominate several sickness conditions much as mortal and neurodegeneration.4–8 These findings make KMTs an logically target entertain therapeutic involvement and suppress encouraged representation identification on the way out modulators break into these enzymes.
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